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Pharmacodynamic study of axitinib in patients with advanced malignancies assessed with (18)F-3′deoxy-3′fluoro-l-thymidine positron emission tomography/computed tomography

PURPOSE: Rapid disease progression associated with increased tumor proliferation has been observed during withdrawal of anti-angiogenic therapy. We characterize the dynamics of withdrawal flare for axitinib. METHODS: Thirty patients with metastatic solid malignancies received axitinib for 2 weeks, f...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Bruce, Justine Yang, Scully, Peter Colin, Carmichael, Lakeesha L., Eickhoff, Jens C., Perlman, Scott B., Kolesar, Jill Marie, Heideman, Jennifer L., Jeraj, Robert, Liu, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499265/
https://ncbi.nlm.nih.gov/pubmed/26021741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2779-7
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