Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[(18)F]-Fluoro-L-Thymidine ([(18)F]FLT) Positron Emission Tomography (PET)

BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependency on EGFR signaling; thus patients with EGFR-muta...

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Detalhes bibliográficos
Main Authors: Ullrich, Roland T., Zander, Thomas, Neumaier, Bernd, Koker, Mirjam, Shimamura, Takeshi, Waerzeggers, Yannic, Borgman, Christa L., Tawadros, Samir, Li, Hongfeng, Sos, Martin L., Backes, Heiko, Shapiro, Geoffrey I., Wolf, Jürgen, Jacobs, Andreas H., Thomas, Roman K., Winkeler, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592703/
https://ncbi.nlm.nih.gov/pubmed/19079597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003908
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