Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[(18)F]-Fluoro-L-Thymidine ([(18)F]FLT) Positron Emission Tomography (PET)

BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependency on EGFR signaling; thus patients with EGFR-muta...

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Main Authors: Ullrich, Roland T., Zander, Thomas, Neumaier, Bernd, Koker, Mirjam, Shimamura, Takeshi, Waerzeggers, Yannic, Borgman, Christa L., Tawadros, Samir, Li, Hongfeng, Sos, Martin L., Backes, Heiko, Shapiro, Geoffrey I., Wolf, Jürgen, Jacobs, Andreas H., Thomas, Roman K., Winkeler, Alexandra
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592703/
https://ncbi.nlm.nih.gov/pubmed/19079597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003908
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