Pharmacodynamic study using FLT PET/CT in advanced solid malignancies treated with a sequential combination of X-82 and docetaxel

BACKGROUND: A sequential approach, synchronizing cell-cycle specific chemotherapy during VEGFR-TKI treatment breaks, may improve the therapeutic index of this combination therapy. In this study we investigate the safety/tolerability and pharmacodynamic effects of docetaxel used in sequential combina...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Scarpelli, Matthew, Rampurwala, Murtuza, Eickhoff, Jens, Carmichael, Lakeesha, Heideman, Jennifer, Binger, Kimberly, Kolesar, Jill, Perlman, Scott, Harrow, Kim, Dukart, Gary, Liang, Chris, Jeraj, Robert, Liu, Glenn, Bruce, Justine Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205037/
https://ncbi.nlm.nih.gov/pubmed/29802443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3599-3
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