(18)F-FLT PET/CT imaging in patients with advanced solid malignancies treated with axitinib on an intermittent dosing regimen

PURPOSE: This study utilizes FLT PET/CT imaging to characterize changes in tumor cell proliferation and vasculature during intermittent treatment with VEGR-TKI axitinib. METHODS: Patients with metastatic solid malignancies underwent 3-week treatment cycles with axitinib (7 and 5 mg BID for safety an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Chemother Pharmacol
Main Authors: Scarpelli, Matthew, Bruce, Justine Yang, Carmichael, Lakeesha, Eickhoff, Jens, Kolesar, Jill, Perlman, Scott, Jeraj, Robert, Liu, Glenn
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209788/
https://ncbi.nlm.nih.gov/pubmed/27817059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3183-7
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