Intermittent dosing of axitinib combined with chemotherapy is supported by (18)FLT-PET in gastrointestinal tumours

BACKGROUND: We evaluated week-on/week-off axitinib dosing plus chemotherapy in patients with gastrointestinal tumours, including tumour thymidine uptake by fluorine-18 3′-deoxy-3′-fluorothymidine positron emission tomography ((18)FLT-PET). METHODS: During a lead-in period, patients received twice da...

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Autori principali: Hoh, C K, Burris, H A, Bendell, J C, Tarazi, J, Rosbrook, B, Kim, S, Infante, J R, Reid, T R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929885/
https://ncbi.nlm.nih.gov/pubmed/24423921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.806
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