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Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms
DNA polymerases maintain genomic integrity by copying DNA with high fidelity. A conformational change important for fidelity is the motion of the polymerase fingers subdomain from an open to a closed conformation upon binding of a complementary nucleotide. We previously employed intra-protein single...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499156/ https://ncbi.nlm.nih.gov/pubmed/26013816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv547 |
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