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Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells
DNA methylation is thought to induce transcriptional silencing through the combination of two mechanisms: the repulsion of transcriptional activators unable to bind their target sites when methylated, and the recruitment of transcriptional repressors with specific affinity for methylated DNA. The Me...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499136/ https://ncbi.nlm.nih.gov/pubmed/26007656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv508 |
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