Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells

DNA methylation is thought to induce transcriptional silencing through the combination of two mechanisms: the repulsion of transcriptional activators unable to bind their target sites when methylated, and the recruitment of transcriptional repressors with specific affinity for methylated DNA. The Me...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Devailly, Guillaume, Grandin, Mélodie, Perriaud, Laury, Mathot, Pauline, Delcros, Jean-Guy, Bidet, Yannick, Morel, Anne-Pierre, Bignon, Jean-Yves, Puisieux, Alain, Mehlen, Patrick, Dante, Robert
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Gene regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499136/
https://ncbi.nlm.nih.gov/pubmed/26007656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv508
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items