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From bacterial to human dihydrouridine synthase: automated structure determination
The reduction of uridine to dihydrouridine at specific positions in tRNA is catalysed by dihydrouridine synthase (Dus) enzymes. Increased expression of human dihydrouridine synthase 2 (hDus2) has been linked to pulmonary carcinogenesis, while its knockdown decreased cancer cell line viability, sugge...
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| Publicado no: | Acta Crystallogr D Biol Crystallogr |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498606/ https://ncbi.nlm.nih.gov/pubmed/26143927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715009220 |
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