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Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase

Dihydrouridine synthases catalyse the reduction of uridine to dihydrouridine in the D-loop and variable loop of tRNA. The human dihydrouridine synthase HsDus2L has been implicated in the development of pulmonary carcinogenesis. Here, the purification, crystallization and preliminary X-ray characteri...

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Detalhes bibliográficos
Main Authors: Griffiths, Sam, Byrne, Robert T., Antson, Alfred A., Whelan, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310545/
https://ncbi.nlm.nih.gov/pubmed/22442237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112003831
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