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Molecular evolution of dihydrouridine synthases

BACKGROUND: Dihydrouridine (D) is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea. Despite the abundant occurrence of D, little is known about its biochemical roles in mediating tRNA function. It is assumed that D may destabilize the struct...

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Detalhes bibliográficos
Main Authors: Kasprzak, Joanna M, Czerwoniec, Anna, Bujnicki, Janusz M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674756/
https://ncbi.nlm.nih.gov/pubmed/22741570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-153
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