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Activation-Induced Cytidine Deaminase Initiates Immunoglobulin Gene Conversion and Hypermutation by a Common Intermediate

Depending on the species and the lymphoid organ, activation-induced cytidine deaminase (AID) expression triggers diversification of the rearranged immunoglobulin (Ig) genes by pseudo V (ψV) gene- templated gene conversion or somatic hypermutation. To investigate how AID can alternatively induce reco...

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Bibliografski detalji
Izdano u:PLoS Biol
Glavni autori: Arakawa, Hiroshi, Saribasak, Huseyin, Buerstedde, Jean-Marie
Format: Artigo
Jezik:Inglês
Izdano: PLOS 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020179
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