A Role for PCNA Ubiquitination in Immunoglobulin Hypermutation

Proliferating cell nuclear antigen (PCNA) is a DNA polymerase cofactor and regulator of replication-linked functions. Upon DNA damage, yeast and vertebrate PCNA is modified at the conserved lysine K164 by ubiquitin, which mediates error-prone replication across lesions via translesion polymerases. W...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Arakawa, Hiroshi, Moldovan, George-Lucian, Saribasak, Huseyin, Saribasak, Nesibe Nur, Jentsch, Stefan, Buerstedde, Jean-Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2006
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618868/
https://ncbi.nlm.nih.gov/pubmed/17105346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040366
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge