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Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neuron-like cells. Mutations in the RNA- and DNA-binding proteins, fused in sarcoma (FUS) and transactive response DNA-binding protein 43 kDa (TDP-43), are responsible for 5–10% of familial and 1% o...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498158/ https://ncbi.nlm.nih.gov/pubmed/25792726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv104 |
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