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Structure and Regulation of the Movement of Human Myosin VIIA

Human myosin VIIA (HM7A) is responsible for human Usher syndrome type 1B, which causes hearing and visual loss in humans. Here we studied the regulation of HM7A. The actin-activated ATPase activity of full-length HM7A (HM7AFull) was lower than that of tail-truncated HM7A (HM7AΔTail). Deletion of the...

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Pubblicato in:J Biol Chem
Autori principali: Sakai, Tsuyoshi, Jung, Hyun Suk, Sato, Osamu, Yamada, Masafumi D., You, Dong-Ju, Ikebe, Reiko, Ikebe, Mitsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498092/
https://ncbi.nlm.nih.gov/pubmed/26001786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599365
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