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The tail binds to the head–neck domain, inhibiting ATPase activity of myosin VIIA
Myosin VIIA is an unconventional myosin, responsible for human Usher syndrome type 1B, which causes hearing and visual loss. Here, we studied the molecular mechanism of regulation of myosin VIIA, which is currently unknown. Although it was originally thought that myosin VIIA is a dimeric myosin, our...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688991/ https://ncbi.nlm.nih.gov/pubmed/19423668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812930106 |
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