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Structure and Regulation of the Movement of Human Myosin VIIA

Human myosin VIIA (HM7A) is responsible for human Usher syndrome type 1B, which causes hearing and visual loss in humans. Here we studied the regulation of HM7A. The actin-activated ATPase activity of full-length HM7A (HM7AFull) was lower than that of tail-truncated HM7A (HM7AΔTail). Deletion of the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sakai, Tsuyoshi, Jung, Hyun Suk, Sato, Osamu, Yamada, Masafumi D., You, Dong-Ju, Ikebe, Reiko, Ikebe, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498092/
https://ncbi.nlm.nih.gov/pubmed/26001786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599365
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