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Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas

Abdominal aortic aneurysms (AAAs) cause death due to complications related to expansion and rupture. The underlying mechanisms that drive AAA development remain largely unknown. We recently described evidence for a shift toward T helper type 2 (Th2) cell responses in human AAAs compared with stenoti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shimizu, Koichi, Shichiri, Masayoshi, Libby, Peter, Lee, Richard T., Mitchell, Richard N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC449742/
https://ncbi.nlm.nih.gov/pubmed/15254597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419855
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