Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas

Abdominal aortic aneurysms (AAAs) cause death due to complications related to expansion and rupture. The underlying mechanisms that drive AAA development remain largely unknown. We recently described evidence for a shift toward T helper type 2 (Th2) cell responses in human AAAs compared with stenoti...

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Bibliographic Details
Main Authors: Shimizu, Koichi, Shichiri, Masayoshi, Libby, Peter, Lee, Richard T., Mitchell, Richard N.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC449742/
https://ncbi.nlm.nih.gov/pubmed/15254597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419855
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