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Probing Reversible Chemistry in Coenzyme B(12)-Dependent Ethanolamine Ammonia Lyase with Kinetic Isotope Effects
Coenzyme B(12)-dependent enzymes such as ethanolamine ammonia lyase have remarkable catalytic power and some unique properties that enable detailed analysis of the reaction chemistry and associated dynamics. By selectively deuterating the substrate (ethanolamine) and/or the β-carbon of the 5′-deoxya...
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| Publicado no: | Chemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497352/ https://ncbi.nlm.nih.gov/pubmed/25950663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201500958 |
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