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Fast Proton Exchange in Histidine: Measurement of Rate Constants through Indirect Detection by NMR Spectroscopy

Owing to its imidazole side chain, histidine participates in various processes such as enzyme catalysis, pH regulation, metal binding, and phosphorylation. The determination of exchange rates of labile protons for such a system is important for understanding its functions. However, these rates are t...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Sehgal, Akansha Ashvani, Duma, Luminita, Bodenhausen, Geoffrey, Pelupessy, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497323/
https://ncbi.nlm.nih.gov/pubmed/24719307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201304992
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