DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in Humans

The (p)ppGpp-mediated stringent response is important for bacterial survival in nutrient limiting conditions. For maximal effect, (p)ppGpp interacts with the cofactor DksA, which stabilizes (p)ppGpp's interaction with RNA polymerase. We previously demonstrated that (p)ppGpp was required for the...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Infect Immun
Κύριοι συγγραφείς: Holley, Concerta L., Zhang, Xinjun, Fortney, Kate R., Ellinger, Sheila, Johnson, Paula, Baker, Beth, Liu, Yunlong, Janowicz, Diane M., Katz, Barry P., Munson, Robert S., Spinola, Stanley M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2015
Θέματα:
Molecular Pathogenesis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496623/
https://ncbi.nlm.nih.gov/pubmed/26056381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00692-15
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