DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in Humans

The (p)ppGpp-mediated stringent response is important for bacterial survival in nutrient limiting conditions. For maximal effect, (p)ppGpp interacts with the cofactor DksA, which stabilizes (p)ppGpp's interaction with RNA polymerase. We previously demonstrated that (p)ppGpp was required for the...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Holley, Concerta L., Zhang, Xinjun, Fortney, Kate R., Ellinger, Sheila, Johnson, Paula, Baker, Beth, Liu, Yunlong, Janowicz, Diane M., Katz, Barry P., Munson, Robert S., Spinola, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496623/
https://ncbi.nlm.nih.gov/pubmed/26056381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00692-15
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