Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis

The defense of cell volume against excessive shrinkage or swelling is a requirement for cell function and organismal survival. Cell swelling triggers a coordinated homeostatic response termed regulatory volume decrease (RVD), resulting in K(+) and Cl(−) efflux via activation of K(+) channels, volume...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Adragna, Norma C., Ravilla, Nagendra B., Lauf, Peter K., Begum, Gulnaz, Khanna, Arjun R., Sun, Dandan, Kahle, Kristopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496573/
https://ncbi.nlm.nih.gov/pubmed/26217182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00255
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