Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis

מאת Adragna, Norma C., Ravilla, Nagendra B., Lauf, Peter K., Begum, Gulnaz, Khanna, Arjun R., Sun, Dandan, Kahle, Kristopher T.
הוצא לאור ב Front Cell Neurosci (2015)

K-Cl cotransporters, cell volume homeostasis, and neurological disease

מאת Kahle, Kristopher T., Khanna, Arjun R., Alper, Seth L., Adragna, Norma C., Lauf, Peter K., Sun, Dandan, Delpire, Eric
הוצא לאור ב Trends Mol Med (2015)

Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia

מאת Merner, Nancy D., Chandler, Madison R., Bourassa, Cynthia, Liang, Bo, Khanna, Arjun R., Dion, Patrick, Rouleau, Guy A., Kahle, Kristopher T.
הוצא לאור ב Front Cell Neurosci (2015)

Changes in the left temporal microstate are a sign of cognitive decline in patients with Alzheimer’s disease

מאת Musaeus, Christian S., Engedal, Knut, Høgh, Peter, Jelic, Vesna, Khanna, Arjun R., Kjær, Troels Wesenberg, Mørup, Morten, Naik, Mala, Oeksengaard, Anne‐Rita, Santarnecchi, Emiliano, Snaedal, Jon, Wahlund, Lars‐Olof, Waldemar, Gunhild, Andersen, Birgitte B.
הוצא לאור ב Brain Behav (2020)

Functional kinomics establishes a critical node of volume-sensitive cation-Cl(−) cotransporter regulation in the mammalian brain

מאת Zhang, Jinwei, Gao, Geng, Begum, Gulnaz, Wang, Jinhua, Khanna, Arjun R., Shmukler, Boris E., Daubner, Gerrit M., de los Heros, Paola, Davies, Paul, Varghese, Joby, Bhuiyan, Mohammad Iqbal H., Duan, Jinjing, Zhang, Jin, Duran, Daniel, Alper, Seth L., Sun, Dandan, Elledge, Stephen J., Alessi, Dario R., Kahle, Kristopher T.
הוצא לאור ב Sci Rep (2016)

WNK1/HSN2 kinase inhibition ameliorates neuropathic pain by reducing maladaptive KCC2 inhibitory phosphorylation and restoring GABA inhibition

מאת Kahle, Kristopher T., Schmouth, Jean-François, Lavastre, Valérie, Latremoliere, Alban, Zhang, Jinwei, Andrews, Nick, Laganière, Janet, Rochefort, Daniel, Hince, Pascale, Castonguay, Geneviève, Gaudet, Rébecca, Mapplebeck, Josiane C.S., Sotocinal, Susana G., Duan, JingJing, Ward, Catherine, Khanna, Arjun R., Mogil, Jeffrey S., Dion, Patrick A., Woolf, Clifford J., Inquimbert, Perrine, Rouleau, Guy A.
הוצא לאור ב Sci Signal (2016)