Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis. An inflammatory microenvironment triggers the pronounced desmoplasia, the selection of cancer stem-like cells (CSCs) and therapy resistance. The anti-inflammatory drug aspirin is suggested to lower the risk for P...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Zhang, Yiyao, Liu, Li, Fan, Pei, Bauer, Nathalie, Gladkich, Jury, Ryschich, Eduard, Bazhin, Alexandr V., Giese, Nathalia A., Strobel, Oliver, Hackert, Thilo, Hinz, Ulf, Gross, Wolfgang, Fortunato, Franco, Herr, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496413/
https://ncbi.nlm.nih.gov/pubmed/25846752
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