Ormeloxifene Suppresses Desmoplasia and Enhances Sensitivity of Gemcitabine in Pancreatic Cancer

The management of pancreatic ductal adenocarcinoma (PDAC) is extremely poor due to lack of an efficient therapy and development of chemoresistance to the current standard therapy, gemcitabine (GEM). Recent studies implicate the intimate reciprocal interactions between epithelia and underlying stroma...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Khan, Sheema, Ebeling, Mara C., Chauhan, Neeraj, Thompson, Paul A., Gara, Rishi K., Ganju, Aditya, Yallapu, Murali M., Behrman, Stephen W., Zhao, Haotian, Zafar, Nadeem, Singh, Man Mohan, Jaggi, Meena, Chauhan, Subhash C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452412/
https://ncbi.nlm.nih.gov/pubmed/25840985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2397
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