Ormeloxifene Suppresses Desmoplasia and Enhances Sensitivity of Gemcitabine in Pancreatic Cancer

The management of pancreatic ductal adenocarcinoma (PDAC) is extremely poor due to lack of an efficient therapy and development of chemoresistance to the current standard therapy, gemcitabine (GEM). Recent studies implicate the intimate reciprocal interactions between epithelia and underlying stroma...

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Vydáno v:Cancer Res
Hlavní autoři: Khan, Sheema, Ebeling, Mara C., Chauhan, Neeraj, Thompson, Paul A., Gara, Rishi K., Ganju, Aditya, Yallapu, Murali M., Behrman, Stephen W., Zhao, Haotian, Zafar, Nadeem, Singh, Man Mohan, Jaggi, Meena, Chauhan, Subhash C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452412/
https://ncbi.nlm.nih.gov/pubmed/25840985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2397
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