Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis. An inflammatory microenvironment triggers the pronounced desmoplasia, the selection of cancer stem-like cells (CSCs) and therapy resistance. The anti-inflammatory drug aspirin is suggested to lower the risk for P...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Zhang, Yiyao, Liu, Li, Fan, Pei, Bauer, Nathalie, Gladkich, Jury, Ryschich, Eduard, Bazhin, Alexandr V., Giese, Nathalia A., Strobel, Oliver, Hackert, Thilo, Hinz, Ulf, Gross, Wolfgang, Fortunato, Franco, Herr, Ingrid
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496413/
https://ncbi.nlm.nih.gov/pubmed/25846752
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