Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis. An inflammatory microenvironment triggers the pronounced desmoplasia, the selection of cancer stem-like cells (CSCs) and therapy resistance. The anti-inflammatory drug aspirin is suggested to lower the risk for P...

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Опубликовано в: :Oncotarget
Главные авторы: Zhang, Yiyao, Liu, Li, Fan, Pei, Bauer, Nathalie, Gladkich, Jury, Ryschich, Eduard, Bazhin, Alexandr V., Giese, Nathalia A., Strobel, Oliver, Hackert, Thilo, Hinz, Ulf, Gross, Wolfgang, Fortunato, Franco, Herr, Ingrid
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496413/
https://ncbi.nlm.nih.gov/pubmed/25846752
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