Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis. An inflammatory microenvironment triggers the pronounced desmoplasia, the selection of cancer stem-like cells (CSCs) and therapy resistance. The anti-inflammatory drug aspirin is suggested to lower the risk for P...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Zhang, Yiyao, Liu, Li, Fan, Pei, Bauer, Nathalie, Gladkich, Jury, Ryschich, Eduard, Bazhin, Alexandr V., Giese, Nathalia A., Strobel, Oliver, Hackert, Thilo, Hinz, Ulf, Gross, Wolfgang, Fortunato, Franco, Herr, Ingrid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496413/
https://ncbi.nlm.nih.gov/pubmed/25846752
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