Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver

Activation of the PI3K and Yes-associated protein (Yap) signaling pathways has been independently reported in human hepatocellular carcinoma (HCC). However, the oncogenic interactions between these two cascades in hepatocarcinogenesis remain undetermined. To assess the consequences of the crosstalk...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xiaolei, Tao, Junyan, Cigliano, Antonio, Sini, Marcella, Calderaro, Julien, Azoulay, Daniel, Wang, Chunmei, Liu, Yan, Jiang, Lijie, Evert, Katja, Demartis, Maria I., Ribback, Silvia, Utpatel, Kirsten, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496343/
https://ncbi.nlm.nih.gov/pubmed/25826091
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