Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms

Podoplanin (PDPN) is a unique transmembrane receptor that promotes tumor cell motility. Indeed, PDPN may serve as a chemotherapeutic target for primary and metastatic cancer cells, particularly oral squamous cell carcinoma (OSCC) cells that cause most oral cancers. Here, we studied how a monoclonal...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ochoa-Alvarez, Jhon A., Krishnan, Harini, Pastorino, John G., Nevel, Evan, Kephart, David, Lee, Joseph J., Retzbach, Edward P., Shen, Yongquan, Fatahzadeh, Mahnaz, Baredes, Soly, Kalyoussef, Evelyne, Honma, Masaru, Adelson, Martin E., Kaneko, Mika K., Kato, Yukinari, Young, Mary Ann, Deluca-Rapone, Lisa, Shienbaum, Alan J., Yin, Kingsley, Jensen, Lasse D., Goldberg, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496201/
https://ncbi.nlm.nih.gov/pubmed/25826087
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