Podoplanin: An emerging cancer biomarker and therapeutic target

Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts and inflammatory macrophages that contribute to cancer progression. In particular, PDPN increases tumor cell clonal capacity, epithelial mesenchymal transition, migratio...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Krishnan, Harini, Rayes, Julie, Miyashita, Tomoyuki, Ishii, Genichiro, Retzbach, Edward P., Sheehan, Stephanie A., Takemoto, Ai, Chang, Yao‐Wen, Yoneda, Kazue, Asai, Jun, Jensen, Lasse, Chalise, Lushun, Natsume, Atsushi, Goldberg, Gary S.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980289/
https://ncbi.nlm.nih.gov/pubmed/29575529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13580
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