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Podoplanin: An emerging cancer biomarker and therapeutic target

Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts and inflammatory macrophages that contribute to cancer progression. In particular, PDPN increases tumor cell clonal capacity, epithelial mesenchymal transition, migratio...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Krishnan, Harini, Rayes, Julie, Miyashita, Tomoyuki, Ishii, Genichiro, Retzbach, Edward P., Sheehan, Stephanie A., Takemoto, Ai, Chang, Yao‐Wen, Yoneda, Kazue, Asai, Jun, Jensen, Lasse, Chalise, Lushun, Natsume, Atsushi, Goldberg, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980289/
https://ncbi.nlm.nih.gov/pubmed/29575529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13580
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