RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation

Previous studies have shown that cervical cancer cells only release low levels of pro-inflammatory cytokines owing to infection with human papillomaviruses. This results in low immunogenicity of the cancer cells. The viral dsRNA analog PolyIC has been suggested as a promising adjuvant for cervical c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schmidt, Susanne V., Seibert, Stefanie, Walch-Rückheim, Barbara, Vicinus, Benjamin, Kamionka, Eva-Maria, Pahne-Zeppenfeld, Jennifer, Solomayer, Erich-Franz, Kim, Yoo-Jin, Bohle, Rainer M., Smola, Sigrun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496172/
https://ncbi.nlm.nih.gov/pubmed/25888634
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