RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis

Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1) and RIPK3 by receptors such as tumor necrosis factor (TNF) receptor-1. Structural studies indicate that activation of RIPK3 by RIPK1 involves the formation of oligomers via...

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Dettagli Bibliografici
Autori principali: Orozco, S, Yatim, N, Werner, M R, Tran, H, Gunja, S Y, Tait, S WG, Albert, M L, Green, D R, Oberst, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158689/
https://ncbi.nlm.nih.gov/pubmed/24902904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.76
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