RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

Necroptosis is a form of programmed cell death that is defined by activation of the kinase RIPK3 and subsequent cell membrane permeabilization by the effector MLKL. RIPK3 activation can also promote immune responses via production of cytokines and chemokines. How active cytokine production is coordi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Orozco, Susana L., Daniels, Brian P., Yatim, Nader, Messmer, Michelle N., Quarato, Giovanni, Chen-Harris, Haiyin, Cullen, Sean P., Snyder, Annelise G., Ralli-Jain, Pooja, Frase, Sharon, Tait, Stephen W.G., Green, Douglas R., Albert, Matthew L., Oberst, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857709/
https://ncbi.nlm.nih.gov/pubmed/31461645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.077
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