RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

Necroptosis is a form of programmed cell death that is defined by activation of the kinase RIPK3 and subsequent cell membrane permeabilization by the effector MLKL. RIPK3 activation can also promote immune responses via production of cytokines and chemokines. How active cytokine production is coordi...

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Publicado no:Cell Rep
Main Authors: Orozco, Susana L., Daniels, Brian P., Yatim, Nader, Messmer, Michelle N., Quarato, Giovanni, Chen-Harris, Haiyin, Cullen, Sean P., Snyder, Annelise G., Ralli-Jain, Pooja, Frase, Sharon, Tait, Stephen W.G., Green, Douglas R., Albert, Matthew L., Oberst, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857709/
https://ncbi.nlm.nih.gov/pubmed/31461645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.077
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