Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates anti-tumor immunity

Although the signaling events that induce different forms of programmed cell death (PCD) are well-defined, the downstream immune responses to dying cells in the context of cancer remain relatively unexplored. Necroptosis occurs downstream of the receptor-interacting protein kinases RIPK1 and RIPK3,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Immunol
Prif Awduron: Snyder, Annelise G., Hubbard, Nicholas W., Messmer, Michelle N., Kofman, Sigal B., Hagan, Cassidy E., Orozco, Susana L., Chiang, Kristy, Daniels, Brian P., Baker, David, Oberst, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831211/
https://ncbi.nlm.nih.gov/pubmed/31227597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw2004
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