Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

Programmed necrosis (or necroptosis) is a form of cell death triggered by the activation of receptor interacting protein kinase-3 (RIPK3). Several reports have implicated mitochondria and mitochondrial reactive oxygen species (ROS) generation as effectors of RIPK3-dependent cell death. Here, we dire...

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Detalhes bibliográficos
Principais autores: Tait, Stephen W.G., Oberst, Andrew, Quarato, Giovanni, Milasta, Sandra, Haller, Martina, Wang, Ruoning, Karvela, Maria, Ichim, Gabriel, Yatim, Nader, Albert, Matthew L., Kidd, Grahame, Wakefield, Randall, Frase, Sharon, Krautwald, Stefan, Linkermann, Andreas, Green, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005921/
https://ncbi.nlm.nih.gov/pubmed/24268776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.034
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