Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

Programmed necrosis (or necroptosis) is a form of cell death triggered by the activation of receptor interacting protein kinase-3 (RIPK3). Several reports have implicated mitochondria and mitochondrial reactive oxygen species (ROS) generation as effectors of RIPK3-dependent cell death. Here, we dire...

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Bibliographic Details
Main Authors: Tait, Stephen W.G., Oberst, Andrew, Quarato, Giovanni, Milasta, Sandra, Haller, Martina, Wang, Ruoning, Karvela, Maria, Ichim, Gabriel, Yatim, Nader, Albert, Matthew L., Kidd, Grahame, Wakefield, Randall, Frase, Sharon, Krautwald, Stefan, Linkermann, Andreas, Green, Douglas R.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005921/
https://ncbi.nlm.nih.gov/pubmed/24268776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.034
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