Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

The pathogenesis of chronic obstructive pulmonary disease (COPD) remains unclear, but involves loss of alveolar surface area (emphysema) and airway inflammation (bronchitis) as the consequence of cigarette smoke (CS) exposure. Previously, we demonstrated that autophagy proteins promote lung epitheli...

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Detalhes bibliográficos
Main Authors: Mizumura, Kenji, Cloonan, Suzanne M., Nakahira, Kiichi, Bhashyam, Abhiram R., Cervo, Morgan, Kitada, Tohru, Glass, Kimberly, Owen, Caroline A., Mahmood, Ashfaq, Washko, George R., Hashimoto, Shu, Ryter, Stefan W., Choi, Augustine M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151233/
https://ncbi.nlm.nih.gov/pubmed/25083992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74985
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