Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

The pathogenesis of chronic obstructive pulmonary disease (COPD) remains unclear, but involves loss of alveolar surface area (emphysema) and airway inflammation (bronchitis) as the consequence of cigarette smoke (CS) exposure. Previously, we demonstrated that autophagy proteins promote lung epitheli...

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Autori principali: Mizumura, Kenji, Cloonan, Suzanne M., Nakahira, Kiichi, Bhashyam, Abhiram R., Cervo, Morgan, Kitada, Tohru, Glass, Kimberly, Owen, Caroline A., Mahmood, Ashfaq, Washko, George R., Hashimoto, Shu, Ryter, Stefan W., Choi, Augustine M.K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151233/
https://ncbi.nlm.nih.gov/pubmed/25083992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74985
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