TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis

Mechanistic understanding of the preferential homing of circulating tumor cells to bone and their perturbation on bone metabolism within the tumor–bone microenvironment remains poorly understood. Alteration in both transforming growth factor β (TGFβ) signaling and sphingolipid metabolism results in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bonekey Rep
Egile Nagusiak: Stayrook, Keith R, Mack, Justin K, Cerabona, Donna, Edwards, Daniel F, Bui, Hai H, Niewolna, Maria, Fournier, Pierrick GJ, Mohammad, Khalid S, Waning, David L, Guise, Theresa A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495778/
https://ncbi.nlm.nih.gov/pubmed/26157579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2015.88
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