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The somatic autosomal mutation matrix in cancer genomes

DNA damage in somatic cells originates from both environmental and endogenous sources, giving rise to mutations through multiple mechanisms. When these mutations affect the function of critical genes, cancer may ensue. Although identifying genomic subsets of mutated genes may inform therapeutic opti...

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Bibliografische gegevens
Gepubliceerd in:Hum Genet
Hoofdauteurs: Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Vasquez, Karen M., Cooper, David N., Mudunuri, Uma, Ivanic, Joseph, Cer, Regina Z., Yi, Ming, Stephens, Robert M., Collins, Jack R., Luke, Brian T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495249/
https://ncbi.nlm.nih.gov/pubmed/26001532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-015-1566-1
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