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The somatic autosomal mutation matrix in cancer genomes
DNA damage in somatic cells originates from both environmental and endogenous sources, giving rise to mutations through multiple mechanisms. When these mutations affect the function of critical genes, cancer may ensue. Although identifying genomic subsets of mutated genes may inform therapeutic opti...
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Publicado no: | Hum Genet |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495249/ https://ncbi.nlm.nih.gov/pubmed/26001532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-015-1566-1 |
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