Loading...

The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

Methylation of cytosine at the 5-carbon position (5mC) is observed in both prokaryotes and eukaryotes. In humans, DNA methylation at CpG sites plays an important role in gene regulation and has been implicated in development, gene silencing, and cancer. In addition, the CpG dinucleotide is a known h...

Full description

Saved in:
Bibliographic Details
Main Authors: Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Luke, Brian T., Collins, Jack R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328458/
https://ncbi.nlm.nih.gov/pubmed/22530050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035558
Tags: Add Tag
No Tags, Be the first to tag this record!