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The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

Methylation of cytosine at the 5-carbon position (5mC) is observed in both prokaryotes and eukaryotes. In humans, DNA methylation at CpG sites plays an important role in gene regulation and has been implicated in development, gene silencing, and cancer. In addition, the CpG dinucleotide is a known h...

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Detalles Bibliográficos
Autores principales: Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Luke, Brian T., Collins, Jack R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328458/
https://ncbi.nlm.nih.gov/pubmed/22530050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035558
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