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The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

Methylation of cytosine at the 5-carbon position (5mC) is observed in both prokaryotes and eukaryotes. In humans, DNA methylation at CpG sites plays an important role in gene regulation and has been implicated in development, gene silencing, and cancer. In addition, the CpG dinucleotide is a known h...

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Autori principali: Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Luke, Brian T., Collins, Jack R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328458/
https://ncbi.nlm.nih.gov/pubmed/22530050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035558
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