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Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells
Moderate DNA damage resulting from metabolic activities or sub-lethal doses of exogenous insults may eventually lead to cancer onset. Human 46BR.1G1 cells bear a mutation in replicative DNA ligase I (LigI) which results in low levels of replication-dependent DNA damage. This replication stress elici...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495043/ https://ncbi.nlm.nih.gov/pubmed/26151554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130561 |
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