Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling

O-GlcNAcylation is a reversible post-translational modification. O-GlcNAc addition and removal is catalyzed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), respectively. More recent evidence indicates that regulation of O-GlcNAcylation is important for inflammatory diseases and tumorigenesis. I...

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Vydáno v:Oncotarget
Hlavní autoři: Yang, Yong Ryoul, Kim, Dae Hyun, Seo, Young-Kyo, Park, Dohyun, Jang, Hyun-Jun, Choi, Soo Youn, Lee, Yong Hwa, Lee, Gyun Hui, Nakajima, Kazuki, Taniguchi, Naoyuki, Kim, Jung-Min, Choi, Eun-Jeong, Moon, Hyo Youl, Kim, Il Shin, Choi, Jang Hyun, Lee, Ho, Ryu, Sung Ho, Cocco, Lucio, Suh, Pann-Ghill
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494956/
https://ncbi.nlm.nih.gov/pubmed/25915426
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