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Formal Asymmetric Hydrobromination of Styrenes via Copper-Catalyzed 1,3-Halogen Migration

An enantioselective Cu(I)-catalyzed 1,3-halogen migration reaction accomplishes a formal hydrobromination by transferring a bromine activating group from a sp(2) carbon to a benzylic carbon in good er and with concomitant borylation of the Ar-Br bond. Computational modelling aids in understanding th...

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發表在:Chem Sci
Main Authors: Van Hoveln, R. J., Schmid, S. C., Tretbar, M., Buttke, C. T., Schomaker, J. M.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494760/
https://ncbi.nlm.nih.gov/pubmed/26167268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC02040E
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