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Asymmetric Palladium-Catalyzed Directed Intermolecular Fluoroarylation of Styrenes

[Image: see text] A mild catalytic asymmetric direct fluoro-arylation of styrenes has been developed. The palladium-catalyzed three-component coupling of Selectfluor, a styrene and a boronic acid, provides chiral monofluorinated compounds in good yield and in high enantiomeric excess. A mechanism pr...

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Detalhes bibliográficos
Main Authors: Talbot, Eric P. A., Fernandes, Talita de A., McKenna, Jeffrey M., Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971964/
https://ncbi.nlm.nih.gov/pubmed/24617344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412881j
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