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PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer

The phosphodiesterase 5 (PDE5) inhibitors, including sildenafil (Viagra™), vardenafil (Levitra™), and tadalafil (Cialis™) have been developed for treatment of erectile dysfunction. Moreover, sildenafil and tadalafil are used for the management of pulmonary arterial hypertension in patients. Since ou...

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Bibliographic Details
Published in:Pharmacol Ther
Main Authors: Das, Anindita, Durrant, David, Salloum, Fadi N, Xi, Lei, Kukreja, Rakesh C
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494657/
https://ncbi.nlm.nih.gov/pubmed/25444755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.10.003
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